(Photo credit: Kelley L Cox-Imagn Images)

Bryce Eldridge launched a walk-off grand slam with no outs in the bottom of the ninth inning as the San Francisco Giants rallied from an eight-run deficit with 10 runs over the final two innings to shock the visiting Washington Nationals 11-10 on Wednesday.

Matt Chapman and Rafael Devers homered as part of a five-run eighth that got the Giants back in the game. San Francisco plated another run in the ninth before Eldridge lofted a towering drive off Mitchell Parker (2-3) to right that barely cleared the brick wall at Oracle Park.

Eldridge, 21, became the youngest player in major league history to hit a walk-off grand slam, 109 days younger than Roberto Clemente when he did it on July 25, 1956.

Nationals starter Foster Griffin took a four-hit shutout into the sixth before Chapman hit his first homer. Griffin allowed one run on six hits over six innings. Reiver Sanmartin (1-0) threw two innings of one-run ball to win his Giants debut.

Pirates 9, Dodgers 8

On a night when Shohei Ohtani pitched, Tyler Callihan stole the show, hitting the first two home runs of his career, including one off Ohtani, to lead host Pittsburgh to a comeback win over Los Angeles.

Callihan's three-run homer in the eighth off Kyle Hurt (1-1) put the Pirates ahead 7-6 to complete a comeback from a 6-1 deficit and snap a four-game losing streak. Spencer Horwitz gave Pittsburgh some insurance later in the inning with a two-run homer. Evan Sisk (1-0) picked up a key out in the top of the eighth to record the win.

Ohtani, who had allowed only one run in his previous four starts, gave up four runs (three earned) on six hits over 6 2/3 innings. He also smashed a homer in the ninth. Ryan Ward staked the Dodgers to a 6-1 lead with his first career grand slam.

Angels 3, Astros 2 (10 innings)

Jose Siri singled in automatic runner Nick Madrigal from third in the bottom of the 10th to give Los Angeles a walk-off victory over visiting Houston in the decisive game of a three-game series.

Logan O'Hoppe went 2-for-2 with a home run and Mike Trout homered, walked and stole a base for the Angels. Reid Detmers allowed just one run on one hit over seven innings, and Ryan Zeferjahn (3-3) pitched a hitless 10th inning.

Shay Whitcomb and Cam Smith homered for the Astros, who finished with just four hits. Peter Lambert allowed two runs on five hits over 6 1/3 innings. Bryan Abreu (2-3) allowed Siri's single.

Rangers 6, Royals 4 (10 innings)

Jake Burger came off the bench and tied the game twice, with a homer and a sacrifice fly, and visiting Texas also took advantage of nine walks allowed by Kansas City to win in 10 innings.

Elias Diaz had a tiebreaking double and Josh Jung drew a bases-loaded walk against Alex Lange (0-3) in the 10th as the Rangers evened the three-game set. Burger, stepping in after Joc Pederson exited due to a sore left hip, delivered with two hits in a game that featured 27 runners left on base.

Rangers reliever Jakob Junis (1-1) threw two scoreless innings. Jac Caglianone had four hits for the Royals, who loaded the bases against Jacob Latz (10 saves) in the 10th but failed to score.

Rockies 3, Cubs 2

Sterlin Thompson lined a pinch-hit single in the ninth inning off Daniel Palencia (1-1) to drive home the winning run, lifting Colorado past Chicago in Denver.

TJ Rumfield homered among his two hits and Hunter Goodman and Ezequiel Tovar also had two hits for the Rockies, who have won the first two games of a three-game series.

The Cubs' Ian Happ tied it with a home run leading off the top of the ninth against Antonio Senzatela (6-0). Chicago starter Shota Imanaga threw five shutout innings.

Yankees 8, Guardians 4

Jazz Chisholm Jr. had a two-run triple and three RBIs and Trent Grisham scored three times as visiting New York completed a three-game sweep of Cleveland.

Grisham tripled and provided the go-ahead run on Jose Caballero's sacrifice fly in the sixth inning, when the Yankees scored three times to go up 6-3. Anthony Volpe and Paul Goldschmidt added RBI hits in chasing Guardians starter Parker Messick (6-3).

Messick gave up a career-high five runs (four earned) on five hits over 5 2/3 innings in losing consecutive starts for the first time in his two-year career. New York outscored the Guardians 18-11 during the series, posting its first sweep of Cleveland since April 22-24, 2022.

Athletics 4, Brewers 3

Carlos Cortes and Lawrence Butler each homered in a seventh-inning rally to give the A's a comeback victory over Milwaukee in the deciding game of the three-game series in Las Vegas.

Alika Williams hit his first career homer, a sixth-inning shot that cut the Athletics' deficit to 3-1. Cortes greeted reliever Chad Patrick (3-3) in the seventh with a leadoff homer, and Butler added a two-run shot in the frame. Scott Barlow (2-0) got two outs for the win.

Gary Sanchez and Jackson Chourio went deep for the Brewers. Brandon Sproat limited the A's to a run on four hits in six innings.

Rays 7, Red Sox 5

Drew Rasmussen struck out a career-high 13 batters over seven scoreless innings, and Tampa Bay held on for a win over Boston to complete a sweep in St. Petersburg, Fla.

Rasmussen (6-2) allowed just two hits in the dominant outing, his second straight in which he tossed seven scoreless frames. Nick Fortes went 4-for-4 with three runs to lead the Rays, including doubles in his first two at-bats. Yandy Diaz added a 3-for-5 showing with one run and two RBIs.

The Red Sox plated five runs in the final two innings on a pair of solo homers from Caleb Durbin and a three-run shot from Ceddanne Rafaela. However, Cedric Mullins' two-run homer in the bottom of the eighth proved to be the difference for the Rays.

Padres 5, Reds 4

Fernando Tatis Jr. hit a game-ending solo home run with two outs in the ninth inning as San Diego rallied past visiting Cincinnati.

Gavin Sheets and Samad Taylor each drove in runs in the eighth to tie the score 4-4 as the Padres won for just the fourth time in 16 games. Wandy Peralta (1-0) delivered a scoreless top of the ninth.

JJ Bleday, Eugenio Suarez and Spencer Steer hit home runs for the Reds, who lost their fourth consecutive series. Chase Petty (0-1) served up Tatis' blast.

Marlins 8, Diamondbacks 0

Kyle Stowers and Owen Caissie hit two-out homers in a six-run fourth inning, Otto Lopez had two hits and two RBIs, and host Miami beat Arizona to extend its winning streak to four games.

Liam Hicks and Heriberto Hernandez each had two hits and scored twice for the Marlins. William Kempner (1-0), the third of four Miami pitchers, tossed two innings for his first major league win.

Gabriel Moreno had two of the six hits amassed by the Diamondbacks, who have lost four of five. Ryne Nelson (2-5) permitted seven runs on eight hits in four innings.

Orioles 7, Mariners 2

Brandon Young threw seven shutout innings, Pete Alonso broke a scoreless tie with a sixth-inning home run and Jackson Holliday added a grand slam as Baltimore halted a four-game losing streak by beating visiting Seattle.

Young (5-1) held the Mariners to two hits. Alonso, Leody Taveras and Tyler O'Neill all had two hits for the Orioles, while Alonso and Taveras each scored two runs.

The Mariners, who lost for only the fourth time in the past 15 games, plated their only two runs in the eighth inning on a Julio Rodriguez RBI groundout and a Josh Naylor single. George Kirby (5-6) allowed seven hits and three runs in six innings.

Twins 6, Tigers 4

Byron Buxton hit his team-high 20th home run, a three-run shot, and visiting Minnesota held off Detroit to level the three-game series.

Royce Lewis added a solo homer and Austin Martin scored twice for the Twins, who got at least one hit from every player in the lineup. Minnesota reliever Taylor Rogers (2-3) tossed a scoreless inning, and Yoendrys Gomez escaped a ninth-inning jam to collect his fifth save.

Gleyber Torres had three hits and an RBI for Detroit. Kerry Carpenter supplied a two-run single while Kevin McGonigle walked three times and scored twice. Detroit starter Framber Valdez (3-5) gave up four runs and six hits in five innings.

Phillies 7, Blue Jays 4

Alec Bohm, Bryce Harper and Kyle Schwarber homered to lead Philadelphia to a rubber-match win over host Toronto.

Bohm's three-run shot in the third extended the Phillies' lead to 4-0. Jesus Luzardo (5-4) allowed one run on four hits in 5 2/3 innings. Philadelphia right fielder Adolis Garcia left the game after pulling a muscle in his right shoulder in the seventh inning.

Toronto's Max Scherzer (1-4), making his first start since April 24, struck out the first batter of the game to become the 11th pitcher in major league history to reach 3,500 strikeouts. However, he allowed five runs and five hits in 3 1/3 innings.

Cardinals 9, Mets 2

Jordan Walker went 2-for-5 with four RBIs as St. Louis extended its winning streak to six games with a victory at New York.

Cardinals starter Andre Pallante (7-4) yielded just two runs on three hits in six innings. JJ Wetherholt had three hits while Walker, Alec Burleson and Nelson Velazquez homered for St. Louis.

Mets opener Austin Warren (1-3) gave up two runs in the first inning. Francisco Alvarez's fourth-inning homer accounted for both of New York's runs.

White Sox 2, Braves 1

Davis Martin pitched six shutout innings and Derek Hill and Luisangel Acuna drove in runs in the fourth to boost host Chicago to a victory against Atlanta.

Martin (9-2) scattered six hits. Bryan Hudson overcame a one-out walk in the ninth to notch his third save. Braden Montgomery and Acuna had two hits apiece for the White Sox, who are the first team this season to win the first two games of a series against the Braves.

Atlanta starter Chris Sale (8-5) permitted two runs and six hits in 5 2/3 innings, failing to work six innings for the third straight start.

--Field Level Media